diff --git a/.size-limit.js b/.size-limit.js
index b841667d9d89..35f5ad2e9d5b 100644
--- a/.size-limit.js
+++ b/.size-limit.js
@@ -379,7 +379,7 @@ module.exports = [
   },
   {
     name: '@sentry/node/import (ESM hook with diagnostics-channel injection)',
-    path: ['packages/server-runtime-injection/build/esm/hook.js', 'packages/node/build/import-hook.mjs'],
+    path: 'packages/node/build/import-hook.mjs',
     ignore: [...builtinModules, ...nodePrefixedBuiltinModules],
     gzip: true,
     disablePlugins: ['@size-limit/esbuild'],
diff --git a/dev-packages/e2e-tests/test-applications/nextjs-16-standalone/tests/build-output.test.ts b/dev-packages/e2e-tests/test-applications/nextjs-16-standalone/tests/build-output.test.ts
index 936ff77b6494..3bd1c5956c6a 100644
--- a/dev-packages/e2e-tests/test-applications/nextjs-16-standalone/tests/build-output.test.ts
+++ b/dev-packages/e2e-tests/test-applications/nextjs-16-standalone/tests/build-output.test.ts
@@ -1,5 +1,6 @@
 import { expect, test } from '@playwright/test';
 import { findAbsolutePathImports } from '@sentry-internal/test-utils';
+import { spawnSync } from 'child_process';
 import * as fs from 'fs';
 import * as path from 'path';
 
@@ -14,19 +15,29 @@ test('emits no absolute-path imports into the relocated standalone output', () =
   expect(leaks).toEqual([]);
 });
 
-// Regression test for the bug this app surfaced (JS-3451): `register.ts` reaches the ESM loader
-// hook through `Module.register(...)`, a runtime call `@vercel/nft` cannot trace. The hook was
-// therefore never copied into the standalone output, and channel-based instrumentation failed to
-// register, silently, behind `debug: true`. Asserting on the traced output rather than on emitted
-// telemetry, because Next.js records its server spans through its own wrapping either way, so the
-// tests in `standalone.test.ts` stay green even when channel injection is dead.
-test('traces the orchestrion ESM loader hook into the standalone output', () => {
-  const standaloneDir = path.join(process.cwd(), '.next', 'standalone');
-  const hookSuffix = path.join('@sentry', 'server-runtime-injection', 'build', 'esm', 'hook.js');
+// Regression test for JS-3451 and JS-4067. `register.ts` hands the ESM loader hook to
+// `Module.register()` by runtime path, so the standalone output must ship the hook and everything it
+// loads: first `@vercel/nft` didn't trace the hook at all, then Turbopack shipped it without its
+// imports. Either way channel injection failed to register, silently, behind `debug: true`. This
+// checks the registration marker rather than emitted telemetry, because Next.js records its server
+// spans through its own wrapping either way. The runner's Node takes the `Module.registerHooks` path,
+// which never loads the hook, so force the `Module.register()` path that Node < 24.13 takes.
+test('registers the orchestrion ESM loader hook from the standalone output', () => {
+  const registerSuffix = path.join('@sentry', 'server-runtime-injection', 'build', 'cjs', 'register.js');
+  const registerPath = fs
+    .readdirSync(path.join(process.cwd(), '.next', 'standalone'), { recursive: true, withFileTypes: true })
+    .map(entry => path.join(entry.parentPath, entry.name))
+    .find(file => file.endsWith(registerSuffix));
+  expect(registerPath).toBeDefined();
 
-  const found = fs
-    .readdirSync(standaloneDir, { recursive: true, withFileTypes: true })
-    .some(entry => entry.isFile() && path.join(entry.parentPath, entry.name).endsWith(hookSuffix));
+  const script = `
+    require('node:module').registerHooks = undefined;
+    require(${JSON.stringify(registerPath)}).registerDiagnosticsChannelInjection();
+    const marker = globalThis.__SENTRY__?.__SENTRY_ORCHESTRION__ ?? globalThis.__SENTRY_ORCHESTRION__;
+    process.stdout.write(JSON.stringify(marker));
+  `;
+  const { stdout, status } = spawnSync(process.execPath, ['-e', script], { encoding: 'utf8' });
 
-  expect(found).toBe(true);
+  expect(status).toBe(0);
+  expect(JSON.parse(stdout)).toEqual({ runtime: [] });
 });
diff --git a/packages/server-runtime-injection/package.json b/packages/server-runtime-injection/package.json
index cf44f9bacc4d..0479485a2383 100644
--- a/packages/server-runtime-injection/package.json
+++ b/packages/server-runtime-injection/package.json
@@ -70,7 +70,7 @@
     "lint:fix": "oxlint . --fix --type-aware",
     "lint": "oxlint . --type-aware",
     "lint:types": "oxlint src --type-aware --type-check",
-    "lint:es-compatibility": "es-check es2020 ./build/cjs/*.js && es-check es2020 ./build/esm/*.js --module",
+    "lint:es-compatibility": "es-check es2020 ./build/cjs/*.js && es-check es2020 ./build/esm/*.js --module --not=./build/esm/hook.js && es-check es2022 ./build/esm/hook.js --module",
     "test:unit": "vitest run",
     "test": "vitest run",
     "test:watch": "vitest --watch",
diff --git a/packages/server-runtime-injection/rollup.npm.config.mjs b/packages/server-runtime-injection/rollup.npm.config.mjs
index 49f2ddd2ba89..f51c1256c341 100644
--- a/packages/server-runtime-injection/rollup.npm.config.mjs
+++ b/packages/server-runtime-injection/rollup.npm.config.mjs
@@ -35,7 +35,6 @@ import { makeBaseNPMConfig, makeNPMConfigVariants } from '@sentry-internal/rollu
 // (Turbopack renames it, producing `.require is not a function` crashes in Next.js on Cloudflare). Hoisting is safe here: the vendored graph is closed (nothing
 // optional/missing) and has no require cycles that depend on lazy evaluation.
 const commonJSOptions = { transformMixedEsModules: true, requireReturnsDefault: 'auto', strictRequires: false };
-const commonJSPlugin = commonjs(commonJSOptions);
 
 // Replace `debug` with `src/debug.ts`, which logs through the Sentry logger. `debug` and the
 // `supports-color` it loads read `process.env` at import time, which throws on Deno without env
@@ -71,6 +70,15 @@ const guardTracingDump = {
   },
 };
 
+// The commonjs-converted vendored dependencies import Node builtins as default imports
+// (`require('path')` → default import of `path`), and builtins have no `.default` in CJS — so
+// builtins need `'default'` interop (the module itself is the default export).
+const builtinInterop = id => (id && (id.startsWith('node:') || builtinModules.includes(id)) ? 'default' : 'esModule');
+
+// The vendored dependencies import builtins unprefixed (`import … from 'tty'`), which Deno rejects
+// and vite-node (Node 26) misresolves as a relative path. Emit them `node:`-prefixed.
+const builtinPaths = Object.fromEntries(builtinModules.map(m => [m, `node:${m}`]));
+
 // Bundling files from the repo-root `node_modules` moves rollup's common source ancestor up to the
 // repo root, so `preserveModules` names our own files `packages/server-runtime-injection/src/...` —
 // strip that prefix to keep the `build/cjs/register.js` layout the `exports` map points at. A vendored
@@ -107,29 +115,42 @@ const orchestrionRuntimeHooks = [
 
 export default [
   ...orchestrionRuntimeHooks,
+  // `register.ts` backs `./register` (the Node SDK `require`s it synchronously from `Sentry.init()`).
   ...makeNPMConfigVariants(
     makeBaseNPMConfig({
-      // `register.ts` backs `./register` (the Node SDK `require`s it synchronously from
-      // `Sentry.init()`); `hook.mjs` backs `./hook` (the async `Module.register()` target, loaded on
-      // Node's ESM loader thread, which cannot resolve bare specifiers into the vendored chunks — but
-      // relative imports work, so it shares the ESM build's vendored chunks). `./hook` only maps its
-      // `import` condition, so the `build/cjs` copy is unused.
-      entrypoints: ['src/register.ts', 'src/hook.mjs'],
+      entrypoints: ['src/register.ts'],
       packageSpecificConfig: {
-        plugins: [debugShim, guardTracingDump, commonJSPlugin, thirdPartyLicensePlugin],
+        plugins: [debugShim, guardTracingDump, commonjs(commonJSOptions), thirdPartyLicensePlugin],
         output: {
           exports: 'named',
           preserveModules: true,
           entryFileNames: sanitizedFileNames,
-          // The commonjs-converted vendored dependencies import Node builtins as default imports
-          // (`require('path')` → default import of `path`), and builtins have no `.default` in CJS —
-          // so builtins need `'default'` interop (the module itself is the default export).
-          interop: id => (id && (id.startsWith('node:') || builtinModules.includes(id)) ? 'default' : 'esModule'),
-          // The vendored dependencies import builtins unprefixed (`import … from 'tty'`), which Deno
-          // rejects and vite-node (Node 26) misresolves as a relative path. Emit them `node:`-prefixed.
-          paths: Object.fromEntries(builtinModules.map(m => [m, `node:${m}`])),
+          interop: builtinInterop,
+          paths: builtinPaths,
+        },
+      },
+    }),
+  ),
+  // `hook.mjs` backs `./hook`, the async `Module.register()` target. `register.ts` hands it over by
+  // runtime path, so build tracers ship `build/esm/hook.js` but may treat it as an opaque asset
+  // and skip its imports (Turbopack does). It is therefore one file that imports only Node builtins.
+  // Its vendored dependencies duplicate the ones in the preserved-modules build above. It keeps the
+  // real `debug` rather than `debugShim`: `Module.register()` never runs on Deno, and `src/debug.ts`
+  // would pull in `@sentry/core`'s ESM build.
+  ...makeNPMConfigVariants(
+    makeBaseNPMConfig({
+      entrypoints: ['src/hook.mjs'],
+      packageSpecificConfig: {
+        plugins: [guardTracingDump, commonjs(commonJSOptions), thirdPartyLicensePlugin],
+        output: {
+          exports: 'named',
+          preserveModules: false,
+          entryFileNames: 'hook.js',
+          interop: builtinInterop,
+          paths: builtinPaths,
         },
       },
     }),
+    { emitCjs: false },
   ),
 ];
diff --git a/packages/server-runtime-injection/src/hook.mjs b/packages/server-runtime-injection/src/hook.mjs
index e0f187804615..1a6eeacbedb2 100644
--- a/packages/server-runtime-injection/src/hook.mjs
+++ b/packages/server-runtime-injection/src/hook.mjs
@@ -3,8 +3,7 @@
 // `Module.registerHooks` API isn't available).
 //
 // `Module.register()` loads its target on Node's ESM loader thread, so the target must be a real,
-// on-disk ES module graph — the loader thread cannot resolve bare specifiers into the dependency
-// graph this package bundles away, but it can follow relative imports. This shim is therefore an
-// entrypoint of the regular ESM build (sharing the vendored dependency chunks) and exposed via the
-// `@sentry/server-runtime-injection/hook` subpath.
+// on-disk ES module. It is built into a single file that imports only Node builtins (see
+// `rollup.npm.config.mjs`), because build tracers ship it without following its imports, and is
+// exposed via the `@sentry/server-runtime-injection/hook` subpath.
 export * from '@apm-js-collab/tracing-hooks/hook.mjs';
diff --git a/packages/server-runtime-injection/src/register.ts b/packages/server-runtime-injection/src/register.ts
index b5e73dcfbc05..95c2fa8996e5 100644
--- a/packages/server-runtime-injection/src/register.ts
+++ b/packages/server-runtime-injection/src/register.ts
@@ -301,8 +301,7 @@ export function registerDiagnosticsChannelInjection(): void {
       // own imports are missing.
       let hookPath: string;
       /*! rollup-include-cjs-only */
-      // This file is `build/cjs/register.js`; the loader thread needs the ESM build, which shares
-      // the vendored dependency chunks.
+      // This file is `build/cjs/register.js`; the loader thread needs the ESM build.
       hookPath = join(__dirname, '../esm/hook.js');
       /*! rollup-include-cjs-only-end */
       /*! rollup-include-esm-only */
@@ -329,7 +328,7 @@ export function registerDiagnosticsChannelInjection(): void {
         // This registers a small loader hook before the real one. Its `load` sets
         // `format: 'module'` for every URL inside our ESM build directory and passes all other URLs
         // through unchanged. Hooks registered earlier also apply when Node loads hook modules
-        // registered later, so the real hook and its chunks load as ESM even without the marker.
+        // registered later, so the real hook loads as ESM even without the marker.
         // The loader is inlined as a `data:` URL because Node always loads those as ESM, so it
         // cannot fail the same way and needs no file of its own.
         const esmDirUrl = `${pathToFileURL(dirname(hookPath)).href}/`;
diff --git a/packages/server-runtime-injection/test/hook.test.ts b/packages/server-runtime-injection/test/hook.test.ts
new file mode 100644
index 000000000000..34ab2202b3d7
--- /dev/null
+++ b/packages/server-runtime-injection/test/hook.test.ts
@@ -0,0 +1,82 @@
+import { spawnSync } from 'node:child_process';
+import { cpSync, mkdirSync, mkdtempSync, readFileSync, rmSync } from 'node:fs';
+import { builtinModules } from 'node:module';
+import { join } from 'node:path';
+import { parseModule } from 'meriyah';
+import { afterAll, describe, expect, it } from 'vitest';
+
+/**
+ * `register.ts` hands the ESM loader hook to `Module.register()` by runtime path, so build tracers
+ * ship `build/esm/hook.js` without following its imports (Turbopack on Next.js does this). Anything
+ * the hook imports beyond Node builtins is then missing on the loader thread. Runs against the
+ * built files, so it needs the package built.
+ */
+const buildDir = join(__dirname, '..', 'build');
+
+function collectSpecifiers(node: unknown, specifiers: string[]): void {
+  if (!node || typeof node !== 'object') {
+    return;
+  }
+  if (Array.isArray(node)) {
+    node.forEach(child => collectSpecifiers(child, specifiers));
+    return;
+  }
+  const { type, source } = node as { type?: string; source?: { type?: string; value?: unknown } };
+  if (
+    (type === 'ImportDeclaration' ||
+      type === 'ExportAllDeclaration' ||
+      type === 'ExportNamedDeclaration' ||
+      type === 'ImportExpression') &&
+    source
+  ) {
+    specifiers.push(source.type === 'Literal' ? String(source.value) : '<computed>');
+  }
+  Object.values(node).forEach(child => collectSpecifiers(child, specifiers));
+}
+
+describe('the ESM loader hook', () => {
+  it('imports nothing but Node builtins', () => {
+    const specifiers: string[] = [];
+    collectSpecifiers(parseModule(readFileSync(join(buildDir, 'esm', 'hook.js'), 'utf8')), specifiers);
+
+    const builtins = new Set(builtinModules);
+    const nonBuiltins = specifiers.filter(s => !(s.startsWith('node:') && builtins.has(s.slice('node:'.length))));
+
+    expect(specifiers.length).toBeGreaterThan(0);
+    expect(nonBuiltins).toEqual([]);
+  });
+
+  describe('when a deployment ships only the hook from the ESM build', () => {
+    // The copy sits inside this package so `register.js` still resolves `@sentry/*` from its
+    // `node_modules`.
+    const copyDir = mkdtempSync(join(__dirname, '.hook-only-'));
+    cpSync(join(buildDir, 'cjs'), join(copyDir, 'build', 'cjs'), { recursive: true });
+    mkdirSync(join(copyDir, 'build', 'esm'));
+    cpSync(join(buildDir, 'esm', 'hook.js'), join(copyDir, 'build', 'esm', 'hook.js'));
+
+    afterAll(() => {
+      rmSync(copyDir, { recursive: true, force: true });
+    });
+
+    it('registers it', { timeout: 30_000 }, () => {
+      // Removing `registerHooks` forces the `Module.register()` path, the one that loads the hook on
+      // Node < 24.13, whatever Node version runs the test.
+      const script = `
+        require('node:module').registerHooks = undefined;
+        const { registerDiagnosticsChannelInjection } = require(${JSON.stringify(join(copyDir, 'build', 'cjs', 'register.js'))});
+        registerDiagnosticsChannelInjection();
+        import('data:text/javascript,export default 1').then(() => {
+          const marker = globalThis.__SENTRY__?.__SENTRY_ORCHESTRION__ ?? globalThis.__SENTRY_ORCHESTRION__;
+          process.stdout.write(JSON.stringify(marker));
+        });
+      `;
+
+      const { stdout, stderr } = spawnSync(process.execPath, ['--no-experimental-detect-module', '-e', script], {
+        encoding: 'utf8',
+      });
+
+      expect(stderr).not.toContain('Failed to register diagnostics-channel injection hooks');
+      expect(JSON.parse(stdout)).toEqual({ runtime: [] });
+    });
+  });
+});
diff --git a/packages/server-runtime-injection/test/nftTrace.test.ts b/packages/server-runtime-injection/test/nftTrace.test.ts
index 2aa8ff749dbe..1d7f38d1ed2c 100644
--- a/packages/server-runtime-injection/test/nftTrace.test.ts
+++ b/packages/server-runtime-injection/test/nftTrace.test.ts
@@ -21,14 +21,11 @@ async function traceFrom(entry: string): Promise<Set<string>> {
 }
 
 describe.each(['cjs', 'esm'])('the %s build', variant => {
-  it('traces the ESM loader hook and the chunks it imports', { timeout: 60_000 }, async () => {
+  it('traces the ESM loader hook', { timeout: 60_000 }, async () => {
     const traced = await traceFrom(`${buildDir}/${variant}/register.js`);
 
     expect(traced).toContain(`${buildDir}/esm/hook.js`);
     // The hook is ESM. Without this marker the loader thread parses it as CommonJS and fails.
     expect(traced).toContain(`${buildDir}/esm/package.json`);
-    // The hook re-exports the vendored chain, so its presence alone would not prove the tracer
-    // followed the hook's own imports rather than copying it as an opaque asset.
-    expect(traced).toContain(`${buildDir}/esm/vendored/@apm-js-collab/tracing-hooks/hook.js`);
   });
 });